Green Synthesis of Schiff Bases by Using Natural Acid Catalysts

The utilization of green chemistry techniques are dramatically reduces chemical wastes and reaction time as recently have been proven in several organic syntheses and chemical transformations. To illustrate these advantages in the synthesis of organic heterocycles, various environmentally benign protocols that involve greener alternatives have been studied. The objective of present research work has also used green methodologies for synthesis of Schiff bases. Conventionally synthesis of Schiff base is carried out with or without acid catalyst and sometimes by refluxing the mixture of aldehyde (or ketone) and amine in organic medium. Present synthesis involves the use of fruit juice of Citrus limetta, Vitis lanata and aqueous extract of Mangifera indica as natural acid catalysts. The synthesized product was identified by its physical properties, melting point, TLC and characterized by Mass spectrometry. Compared with traditional methods, these methods were more convenient and provided higher yield (75-93%), shows maximum efficiency, held without generation of pollution in shorter reaction time, safer to analyst, low cost and simple to run.